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Background: Method comparison tools are used to determine the accuracy, precision, agreement and clinical relevance of a new or improved technology versus a reference technology. Guidelines for the most appropriate method comparison tools as well as their acceptable limits are lacking and not standardised for CD4 counting technologies. Methods: Different method comparison tools were applied to a previously published CD4 data set (n= 150 data pairs) evaluating five different CD4 counting technologies (TruCOUNT, Dual Platform, FACSCount, Easy CD4, CyFlow) on a single specimen. Bland-Altman, percentage similarity, percent difference, concordance correlation, sensitivity, specificity and misclassification method comparison tools were applied as well as visualization of agreement with Passing Bablock and Bland-Altman scatter plots. Results: The FACSCount (median CD4 = 245cells/µl) was considered the reference for method comparison. NewsCSAC RSS
Workshop Standardization in multicolor cytometry 18. 04. 2017

24. konference European cell death organization (ECDO) se konala 28. - 30. září 2016 ve španělské Barceloně. Pro její konání byl vybrán Barcelona Biomedical research park umístěný v krásném prostředí přímořské promenády u pláže Barceloneta. Konference nesla podtitul „Cell Death in Health and Disease“ a tento rok se na její organizaci podílela evropská organizace COST Action PROTEOSTASIS BM1307

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