SCIENTIFIC PROGRAM & ABSTRACTS

Prague, May 29, 2018


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8:30 – 9:10        Registration

9:10 – 9:15        Opening | Jan Trka, Júlia Starková
9:15 – 12:15        SESSION I
Chairman: Tomáš Mráček

9:15 – 10:00                     abstract
Transcriptional deregulation of metabolism as a hacker of metastasis: decoding the communication networks between tumours and microenvironment
Verónica Torrano, CIC bioGUNE, Derio, Spain

10:00 – 10:30                     abstract
Reactivation of dihydroorotate dehydrogenase by respiration restores tumor growth of mitochondrial DNA-depleted cancer cells
Jakub Rohlena, Institute of Biotechnology, Czech Academy of Sciences, Prague

Short talk:
10:30 – 10:45                     abstract
Functional electron transport chain is necessary for stress resistance in quiescent cells 
Silvia M. Novais, Institute of Biotechnology, Czech Academy of Sciences, Prague

10:45 – 11:15        Coffee break

11:15 – 11:45                     abstract 
Lipids in colon cancer development
Jiřina Hofmanová, Institute of Biophysics, Czech Academy of Sciences, Brno

11:45 – 12:15                     abstract 
Mitochondrial glycerophosphate dehydrogenase as a target for inhibition of cell proliferation in tumors
Alena Pecinová, Institute of Physiology, Czech Academy of Sciences, Prague

12:15 – 13:30        Lunch
13:30 – 14:45        SESSION II
Chairman: Jan Trnka

13:30 – 14:00                     abstract
Altered cellular metabolism in malignant transformation and therapy response in acute leukemias 
Júlia Starková, Second Faculty of Medicine, Charles University, Prague

Short talks:
14:00 – 14:15                     abstract
The metabolic sensor AMPK is a new regulator of oncogene-driven ERK signaling in cancer cells 
Stjepan Uldrijan, Faculty of Medicine, Masaryk University, Brno

14:15 – 14:30                     abstract
Cancer-associated fibroblasts in malignant melanoma
Karel Smetana, First Faculty of Medicine, Charles University, Prague

14:30 – 14:45                     abstract
Mitochondrial 2HG production as a function of IDH2 and HOT in breast cancer cells
Katarína Smolková, Institute of Physiology, CAS, Prague
15:00 – 16:00         MODERATED POSTER SESSION 
Chairman: Verónica Torrano

P1. Lactate as a signaling molecule in the tumor microenvironment
Martina Koncošová, University of Chemistry and Technology, Prague              abstract

P2. Glutamine as a sensitizing factor for the therapy of solid tumors
Nikola Vrzáčková, University of Chemistry and Technology, Prague              abstract

P3. Cancer senescent cells differ from their proliferating counterparts in their response to cell death-inducing agents
Peter Holíček, Institute of Biotechnology, Czech Academy of Sciences, Prague              abstract

P4. Role of metabolism in chemoresistance of neuroblastoma cells
Tomáš Eckschlager, Second Faculty of Medicine, Charles University, Prague              abstract

P5. Common themes in cancer and virus-infected cells
Zora Mělková, First Faculty of Medicine, Charles University, Prague              abstract

P6. Pushing the ERK pathway activity out of the fitness zone with metabolic stressors: new targeted therapy for melanoma?
Barbora Valčíková, Faculty of Medicine, Masaryk University, Brno              abstract

P7. Identification the key players of metabolic reprogramming of leukemic cells upon l-asparaginase treatment
Natividad Alquezar Artieda, Second Faculty of Medicine, Charles University, Prague              abstract

P8. Exploring metformin action on the regulation of cancer cell proliferation
Andrea Brázdová, Institute of Physiology, Czech Academy of Sciences, Prague              abstract
18:00 – 23:00        SOCIAL EVENT



 
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